i am driving for the first from Calais

My recommended route [minimal toll charges] to Italy is as follows;-  [Toll free as far as Switzerland]

1. Calais/Dunkirk to Lillle and on into Belgium  [Unless you are not doing a 'short crossing' to France]
2. Through Belguim to Luxembourg - passing by Mons and Namur
3. Fill up with fuel at services in Luxembourg [cheapest on this route]
4. Down through France past Metz and Nancy to Colmar [or Mulhouse, but I think the road to Colmar is slightly easier]
5. Into Germany and take the autobahn toward Basle
6. Turn off before Basle and take the dual carriage way past Lorrach and into Switzerland [my 'Basle ByePass']
7. Then on Swiss motorway [Vignette needed] past Lucerne and on to the Gotthard Tunnel
8. Through the Tunnel [or over the pass, which I recommend] and on into Italy
9. Then autostrada to Rome/Viterbo

This route is dual carriageway/motorway all the way except for Nancy to Colmar or MulhouseAccommodation is expensive in Switzerland - we tend to avoid 'overnights' there Enjoy..........